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The cleft nose and reconstruction

A cleft nose is a sequence spread across a childhood: a repair at three months, sometimes a second at five or six, and a definitive rhinoplasty once the face has finished growing. The argument in this literature is how much to do at each stage, since operating early was long feared to stunt the nose and operating late means a child grows up with a visibly asymmetric face. The evidence now says the fear was largely wrong: eight of nine studies that measured growth found no restriction, and between 43% and 100% of children who had a primary rhinoplasty avoided a revision later.

Where these 171 papers were published

  • 54Plastic and Reconstructive SurgeryPlast Reconstr Surg
  • 35Aesthetic Plastic SurgeryAesthetic Plast Surg
  • 21Facial Plastic SurgeryFacial Plast Surg
  • 19Aesthetic Surgery JournalAesthet Surg J
  • 17Plastic and Reconstructive Surgery Global OpenPlast Reconstr Surg Glob Open
  • 9JAMA Facial Plastic SurgeryJAMA Facial Plast Surg
  • 7Facial Plastic Surgery and Aesthetic MedicineFacial Plast Surg Aesthet Med
  • 5Facial Plastic Surgery Clinics of North AmericaFacial Plast Surg Clin North Am
  • 3Archives of Facial Plastic SurgeryArch Facial Plast Surg
  • 1Clinics in Plastic SurgeryClin Plast Surg

49 further papers on this topic came in through the history rather than the archive query: GOLDMAN IB 1957, Sheen JH 1984, Furlan S 1995, Santoni-Rugiu P 1997 and 45 more. They are counted on the landmark papers, not here.

What repeats

Six findings reported by independent groups in different countries. Each card carries the papers it rests on.

Operating on the nose during the lip repair does not stunt it

Twenty-five studies systematically reviewed: ten assessed primary rhinoplasty subjectively and all supported it; sixteen assessed it objectively and fifteen supported it; eight of nine studies that specifically examined nasal growth and development found no restriction. Across five studies with at least six years of follow-up, between 43% and 100% of patients avoided a later revision rhinoplasty. Risk of bias was significant in most of those studies, but the direction is unanimous, which is why primary rhinoplasty at the time of lip repair is now standard in most centres.

Rests on: Zelko et al., systematic review of 25 studies · Chong et al., primary rhinoplasty in unilateral cleft lip.

Deliberate overcorrection at the first operation holds for eighteen years

103 children who had primary rhinoplasty with Tajima overcorrection between 2000 and 2005, measured at skeletal maturity against 30 who had primary rhinoplasty without overcorrection and 27 non-cleft controls: the overcorrected group came closest to the controls on FACE-Q satisfaction and on photogrammetric symmetry, and needed no intermediate operation. A separate 146-patient cohort photographed at 1, 5, 10, 15 and 18 years found the residual asymmetry appears early, stays minor and stays stable. Symmetry measured incrementally after primary repair settles by about four months and holds.

Rests on: Murali et al., overcorrection at skeletal maturity · Huang et al., morphology after facial maturation · Abdurrob et al., longitudinal anatomic analysis.

The middle operation is the contested one

Intermediate rhinoplasty, done in mixed dentition, has no consensus behind it. The largest series, 342 patients and 372 operations over eighteen years, found the graft chosen predicted whether another operation followed: an iliac crest cartilage graft independently predicted fewer subsequent rhinoplasties, as did a V-Y chondromucosal flap in unilateral clefts and a columellar strut in bilateral ones. Repositioning the septum at five or six years improved nostril symmetry and caudal deviation at both short and long follow-up. The Tajima reverse-U incision works best in children aged 4 to 13 with mild to moderate deformity, held at five years.

Rests on: Ng et al., eighteen years of intermediate rhinoplasty · Kim et al., septal repositioning at preschool age · Liu et al., the Tajima technique at five years.

At maturity the operation is a structural rhinoplasty with a septal graft at its centre

194 unilateral and 92 bilateral cleft patients operated at skeletal maturity by one surgeon with a reverse-U incision and a septal extension graft: measured in three dimensions, the underprojected, up-rotated, deviated tip and short bridge all moved toward matched normal controls, with a 4% complication rate in the bilateral series. The residual gaps are consistent, nostril height ratio, alar width ratio, and upper lip deficiency, which the nose operation cannot fix.

Rests on: Saito et al., 194 unilateral cases · Saito et al., 92 bilateral cases · Xia et al., nasal sill classification in 276 patients.

The cleft nose is an airway problem as well as a shape problem

Obstruction is present in mild to moderate severity before secondary cleft rhinoplasty and improves measurably after it, in blockage, in trouble breathing and in getting enough air on exertion. The details matter: lateral crural strut grafting was associated with improvement, alar revision and tip sutures with worsening of specific symptoms, and children who had a nasal stent afterwards reported less trouble breathing. A septal cartilage rim graft placed at the primary repair left a measurably straighter septum ten years later.

Rests on: Carlson et al., airway after secondary cleft rhinoplasty · Ueno et al., ten-year septal outcome · Al-Qatami et al., postsurgical nostril retainer.

Reconstruction after collapse follows the same logic, whatever caused it

A nose that has lost its structure (from surgery, trauma, disease or a cleft) is rebuilt on the same principles: assess the lining, assess the skin, then rebuild the framework. A 60-patient saddle-nose algorithm sorts the deformity into four types, records septal perforation in 10%, and treats the mucosal lining as decisive; where the skin envelope is contracted, filler has been used to expand it before reconstructing underneath. Total skeletal reconstruction after multiple failed rhinoplasties, a mean of 3.2 previous operations in 25 patients, improved both breathing and appearance scores. Preservation principles have now been applied even here, with a reverse spare roof technique for the saddle nose.

Rests on: Battista et al., saddle nose algorithm · Sazgar et al., total skeletal reconstruction · Ferreira and Santos, the reverse spare roof technique.

By stage

The cleft nose over a lifetime, and the reconstructive problems that share its methods.

Before surgery: moulding

Presurgical nasoalveolar moulding shapes the cleft nostril before the lip is repaired, and a nostril retainer afterwards holds it. In 50 consecutive children, adding a postsurgical retainer to moulding and primary lip-nose surgery changed measured nasal form against moulding and surgery alone.

Key papers: Al-Qatami et al. · Farouk, eighteen years and 800 patients.

Primary rhinoplasty, at the lip repair

Repositioning the alar base, centralising the columella, improving tip projection, minimising trauma. Done through a Tajima reverse-U incision, often with deliberate overcorrection, and, in the current literature, with a septal cartilage graft for rim support and preservation principles borrowed from adult rhinoplasty, including releasing and repositioning the Pitanguy ligament in six infants.

Key papers: Chong et al. · Murali et al. · Ueno et al. · Tanikawa et al., preservation principles in cleft infants.

Intermediate rhinoplasty, in the school years

Done for symmetry before the social cost of the deformity accumulates, argued against because the face is still growing. The eighteen-year series shows it is the graft choice rather than the age that predicts whether another operation follows.

Key papers: Ng et al. · Kim et al. · Liu et al..

Definitive rhinoplasty, at skeletal maturity

An open structural operation: reverse-U incision, septal extension graft, dorsal augmentation, alar base work and often lip revision in the same sitting. Where autologous cartilage is short, irradiated homologous costal cartilage has been used in 96 of 165 cleft rhinoplasties with complication rates comparable to autologous (12% against 10%), though fewer of the homologous complications needed an operation to fix.

Key papers: Saito et al. · Saito et al. · Jenny et al., irradiated homologous cartilage in cleft rhinoplasty.

The nostril, the sill and the alar base

The base-view deformity is what remains visible after everything else is corrected. A 276-patient classification of nasal sill morphology gives it a common language and a technique per type; composite grafts from the ear rebuild an alar-nostril ring destroyed by over-resection; a philtral flap reconstructs a missing columella.

Key papers: Xia et al. · Sazgar et al., alar nostril ring correction · Bastaninejad et al., the philtral flap.

The saddle nose and the collapsed dorsum

Loss of dorsal support from septal surgery, trauma, disease or cocaine. Graded by severity, planned around the lining and the skin, rebuilt with septal, conchal or costal cartilage. And, in the newest report, with preservation logic applied in reverse to raise the roof rather than lower it.

Key papers: Battista et al. · Ferreira and Santos · Sazgar et al..

The incision, in a nose that has been opened before

A prospective comparison of 52 reconstructive rhinoplasties found a V-shaped columella-labial incision with V-Y closure gave greater projection and columellar height than the standard mid-columellar incision with no difference in scar; in 91 multiply operated noses the same incision produced no dehiscence and no vascular event.

Key papers: Sazgar et al., prospective incision comparison · Sazgar et al., 91 compromised noses · Sazgar et al., a preferred incision.

Planning a reconstruction in three dimensions

For craniofacial cases, in-house virtual planning with printed cutting guides and splints helped harvest and shape septal and costochondral grafts accurately and shortened operating time in a children's hospital workflow.

Key paper: Rubio-Palau et al., in-house virtual planning.

The terms, defined

Every term the papers above use to mean something specific, in plain language.

  • Unilateral and bilateral cleft lip nasal deformity: the nose that comes with a cleft lip: on the cleft side the alar base sits low and lateral, the columella is short and deviated, the lower lateral cartilage is flattened and the septum deviates away. [41563425]
  • Primary, intermediate and secondary (definitive) rhinoplasty: the operation done with the lip repair in infancy, the one done in the school years, and the one done at skeletal maturity. Each has its own literature and its own argument. [36409217, 39560597, 37797231]
  • Nasoalveolar moulding (NAM): pre-surgical moulding of the alveolus and nostril in the first weeks of life to narrow the cleft and lift the nostril before surgery. [35787611]
  • Nostril retainer (nasal stent): a splint worn in the nostril after surgery to hold its shape while it heals; associated with better measured form and less reported obstruction. [35787611, 36696324]
  • Tajima reverse-U incision: the standard incision for the cleft nasal tip, used with deliberate overcorrection in the primary operation. [36730430, 38967637]
  • Overcorrection: deliberately setting the cleft-side nostril beyond symmetry at the primary operation, because it relapses toward the middle as the child grows. [36730430, 41949992]
  • V-Y chondromucosal flap: a lining flap used in unilateral cleft correction; independently predicted fewer subsequent operations in the intermediate series. [39560597]
  • Iliac crest cartilage graft: cartilage taken from the pelvis, used in intermediate cleft rhinoplasty; the graft choice associated with fewer further operations. [39560597]
  • Irradiated homologous costal cartilage: sterilised donor rib, used in cleft rhinoplasty to avoid a chest harvest in a child. [33370059]
  • Septal extension graft: the graft fixed to the caudal septum that sets tip projection and rotation; the centre of the definitive cleft operation. [37797231, 38314894]
  • Nasal sill: the floor of the nostril where it meets the lip; classified in four types on the base view to guide secondary correction. [39572464]
  • Saddle nose deformity: collapse of the dorsum from lost septal support, graded by severity, with the mucosal lining and skin condition deciding what can be rebuilt. [42324394]
  • Reverse spare roof technique: preservation logic applied upward: raising a saddled dorsum instead of lowering a humped one. [35357956]
  • Total skeletal reconstruction: rebuilding the entire nasal framework after multiple failed operations, in patients averaging 3.2 previous rhinoplasties. [33506865]
  • Photogrammetric analysis: measuring symmetry from standardised photographs; how most of the long-term cleft outcomes here are quantified. [36730430, 36976783]

The papers this rests on

The 40 papers everything above was written from. Every one links to its abstract, its authors and its DOI.

  1. APS
    2026PMID 42324394Summary
  2. APS
    2025PMID 39572464Summary
  3. PRS
    2023PMID 36409217Summary
  4. ASJ
    2022PMID 34864854Summary
  5. ASJ
    2021PMID 33492387
  6. FPS
    2016PMID 28033640Summary
  7. FPS
    2015PMID 26579870Summary
  8. ASJ
    2026PMID 42415377Summary
  9. APS
    2026PMID 41998166Summary
  10. APS
    2026PMID 41731229Summary
  11. APS
    2026PMID 41535507
  12. APS
    2026PMID 41879850Full text
  13. APS
    2026PMID 42380315Summary
  14. FPS
    2026PMID 39965762Summary
  15. FPSAM
    2026PMID 40019820
  16. FPSAM
    2026PMID 41681113
  17. PRS
    2023PMID 36730430Summary
  18. PRS
    2026PMID 41949992Summary
  19. FPSAM
    2023PMID 36976783Summary
  20. PRS
    2022PMID 35787611Summary
  21. PRS
    2026PMID 41100821Summary
  22. PRS
    2025PMID 39560597Summary
  23. PRS
    2024PMID 37467053Summary
  24. PRS
    2024PMID 37797231Summary
  25. ASJ
    2024PMID 38314894Summary
  26. PRS
    2025PMID 38967637Summary
  27. PRS
    2023PMID 36696324Summary
  28. PRS
    2021PMID 33370059Summary
  29. PRS
    2026PMID 40358520Summary
  30. PRS
    Primary Rhinoplasty in Unilateral Cleft Lip
    Chong DK, Tanikawa DYS, Fell M
    2026PMID 41563425Summary
  31. ASJ
    2025PMID 39161317Summary
  32. ASJ
    2021PMID 33506865Summary
  33. ASJ
    2025PMID 40408098Summary
  34. ASJ
    2025PMID 39676167Summary
  35. FPSAM
    2024PMID 37115534Summary
  36. PRS
    2023PMID 36729933Summary
  37. PRS
    2024PMID 37749799Summary
  38. FPSAM
    2022PMID 35357956Summary
  39. PRS
    2025PMID 41071182Summary
  40. ASJ
    2024PMID 38366551Summary

What is still contested

  • The timing of the intermediate operation has no consensus: the risk-to-benefit balance in mixed dentition is still argued, and the largest series concludes that what is grafted matters more than when. [39560597]
  • The primary-rhinoplasty evidence is unanimous in direction and weak in method, 25 studies with significant risk of bias in most. [36409217]
  • No trial compares overcorrection against no overcorrection prospectively; the eighteen-year evidence is a retrospective cohort with historical comparison groups. [36730430]
  • Homologous against autologous cartilage in children is decided in one 165-case series with a median follow-up of 256 days, short for a graft question. [33370059]
  • Upper lip deficiency persists after every technique measured here, and no nasal operation addresses it. [38314894]
  • Outcome measures differ by centre (FACE-Q, photogrammetry, panel assessment, NOSE), so the long-term series cannot be pooled.
  • The saddle nose and total reconstruction literature is entirely single-surgeon case series; the algorithms are experience, published as algorithms. [42324394, 33506865]

Written by rhinoplasty.cc from the PubMed abstracts, 2026-09-09. Not medical advice.

Related topics

Every paper, by year

171 papers. The 40 above are not repeated.

202616 papers · 14 above
  1. PRS
    PMID 41427759
  2. PRS
    PMID 41880548
202518 papers · 7 above
  1. APS
    PMID 40699341
  2. APS
    PMID 40195130Summary
  3. APS
    PMID 40394313Summary
  4. APS
    PMID 40646255Summary
  5. FPS
    PMID 41338277Summary
  6. FPS Clin
    Comprehensive Cleft Rhinoplasty Throughout Development
    McCracken M, Woldanski L, Neumeister E et al.
    PMID 41101813Summary
  7. PRS-GO
    PMID 39911533Summary
  8. PRS-GO
    PMID 41050978Summary
  9. PRS-GO
    PMID 39816899Summary
  10. PRS-GO
    PMID 40642259Summary
  11. PRS-GO
    PMID 40502425Summary
202417 papers · 6 above
  1. APS
    PMID 37749417Summary
  2. APS
    PMID 39285056Summary
  3. APS
    PMID 38839614Summary
  4. APS
    PMID 38062265Summary
  5. APS
    PMID 37945758Summary
  6. APS
    PMID 37567945Summary
  7. APS
    PMID 38693403Summary
  8. FPS
    PMID 38151040Summary
  9. FPS Clin
    Secondary Cleft Rhinoplasty
    Liao D, Pereira N, Obayemi A Jr et al.
    PMID 37981415Summary
  10. PRS-GO
    PMID 39247573Summary
  11. PRS-GO
    PMID 38957724Summary
202313 papers · 5 above
  1. APS
    PMID 36323963Summary
  2. APS
    PMID 37097454
  3. APS
    PMID 37640816Summary
  4. FPS
    PMID 37433309Summary
  5. FPS
    PMID 36100245Summary
  6. FPS
    PMID 36972604Summary
  7. FPS Clin
    PMID 36396285Summary
  8. PRS-GO
    PMID 37731727Summary
20228 papers · 3 above
  1. CPS
    Cleft Rhinoplasty
    Olds CE, Sykes JM
    PMID 34782130Summary
  2. FPS
    PMID 35158388Summary
  3. PRS
    PMID 36166381
  4. PRS-GO
    PMID 35999875Summary
  5. PRS-GO
    PMID 36381488Summary
202114 papers · 3 above
  1. ASJ
    PMID 33674847
  2. ASJ
    PMID 33821953
  3. APS
    PMID 33811290Summary
  4. APS
    PMID 33507350Summary
  5. APS
    PMID 34075457Full text
  6. APS
    PMID 33837462
  7. FPS
    PMID 33556970Summary
  8. PRS
    PMID 34398093Summary
  9. PRS
    PMID 33764912
  10. PRS
    Secondary Rhinoplasty for Unilateral Cleft Nasal Deformity
    Rohrich RJ, Benkler M, Avashia YJ et al.
    PMID 34076624Summary
  11. PRS-GO
    PMID 34712542Full text
202018 papers
  1. APS
    PMID 31485763Summary
  2. APS
    PMID 31624893
  3. APS
    PMID 32778931Summary
  4. FPS
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    Hoshal SG, Solis RN, Tollefson TT
    PMID 32191966Summary
  5. FPSAM
    PMID 32628569Summary
  6. FPSAM
    PMID 32212970
  7. PRS
    PMID 31985674
  8. PRS
    PMID 31834232
  9. PRS
    PMID 32195860Summary
  10. PRS
    PMID 32332543
  11. PRS
    PMID 32332542Summary
  12. PRS
    PMID 31985675
  13. PRS
    PMID 31834230
  14. PRS
    PMID 33235001
  15. PRS
    PMID 32472910
  16. PRS
    PMID 32097325Summary
  17. PRS
    PMID 31985651Summary
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201910 papers
  1. ASJ
    PMID 29394311Summary
  2. ASJ
    PMID 30107387Summary
  3. APS
    PMID 31263933Summary
  4. APS
    PMID 30868305Summary
  5. FPS
    PMID 31639871Summary
  6. FPS
    PMID 30566988Summary
  7. PRS
    PMID 30601327Summary
  8. PRS
    PMID 31403561
  9. PRS
    PMID 31688761Summary
  10. PRS-GO
    PMID 30881815Full text
201812 papers
  1. ASJ
    PMID 30084887
  2. APS
    PMID 29124376Summary
  3. APS
    PMID 29380021
  4. APS
    PMID 29392358
  5. FPS
    PMID 29857340Summary
  6. JAMA FPS
    PMID 28910438Summary
  7. JAMA FPS
    PMID 30326520Summary
  8. PRS
    PMID 30247379
  9. PRS
    PMID 29608514
  10. PRS
    PMID 28953561
  11. PRS
    PMID 29608516
  12. PRS
    PMID 28938353
20176 papers
  1. ASJ
    PMID 29149246Summary
  2. FPS
    PMID 28388792Summary
  3. PRS
    PMID 28445370
  4. PRS
    PMID 28820829
  5. PRS
    PMID 28098711Summary
  6. PRS
    PMID 28820828
201611 papers · 1 above
  1. FPS
    PMID 27097144Summary
  2. FPS
    Technique in Cleft Rhinoplasty: The Foundation Graft
    Gassner HG, Schwan F, Haubner F et al.
    PMID 27097143Summary
  3. FPS Clin
    PMID 27712813Summary
  4. FPS Clin
    PMID 27712816Summary
  5. JAMA FPS
    PMID 26720547
  6. JAMA FPS
    PMID 26892673Summary
  7. PRS
    PMID 27348671
  8. PRS-GO
    PMID 27536492Summary
  9. PRS-GO
    PMID 27482502Summary
  10. PRS-GO
    PMID 27975028Summary
20158 papers · 1 above
  1. ASJ
    PMID 26116747
  2. ASJ
    PMID 26116748
  3. JAMA FPS
    PMID 25996279
  4. JAMA FPS
    PMID 25996277
  5. JAMA FPS
    PMID 26432958
  6. PRS
    PMID 26505717Summary
  7. PRS-GO
    PMID 26180711Summary
201412 papers
  1. ASJ
    PMID 25028737Summary
  2. APS
    PMID 24357194Summary
  3. FPS
    PMID 24918702Summary
  4. FPS
    PMID 24918706Summary
  5. JAMA FPS
    PMID 24201895Summary
  6. JAMA FPS
    PMID 24458140Summary
  7. PRS
    PMID 24867716Summary
  8. PRS
    PMID 24776545Summary
  9. PRS
    PMID 24776586
  10. PRS
    PMID 25415095Summary
  11. PRS
    PMID 24776585
  12. PRS-GO
    PMID 25289365Summary
20132 papers
  1. ASJ
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  2. FPS
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20124 papers
  1. APS
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  2. Arch FPS
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20112 papers
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